PDD0022 - Ion Channels - COMING SOON

Course Description

Ion channels critically regulate essential physiological processes, underlie numerous acquired and inherited human diseases, and represent important targets for clinically used drugs and emerging experimental tool compounds. The purpose of this course is to introduce students to fundamental concepts in ion channel electrophysiology, including Ohm’s Law, the Nernst Equation, the Goldman-Hodgkin-Katz equation, the Current equation, voltage-clamp electrophysiology, the importance of membrane capacitance, time-constants, and length-constants in neurological function, as well as high-throughput screening methods for discovering novel small-molecule ion channel modulators. Historical and modern research articles illustrating the importance of rigorous and reproducible experimental design and statistical methods and limitations, and quantitative literacy will also be discussed. The course will be taught by Jerod Denton, Ph.D., who is Professor of Anesthesiology, Professor of Pharmacology, and Director of Ion Channel Pharmacology at the Warren Center for Neuroscience Drug Discovery.