PDD0020 - 004. Chemical Synthesis

Course Description

Chemical Synthesis, taught by Craig Lindsley, will discuss chemical synthesis, particularly solution phase parallel synthesis, microwave-assisted organic synthesis (MAOS), and peptide synthesis. Some other topics covered in this course include solid phase organic synthesis, solid supports, polymer and silica-based reagents/scavengers, ion-exchange chromatography (SPE), fluorous-tagged reagents/scavengers, and other applications to total synthesis & drug discovery.

We highly recommend taking the Principles of Medicinal Chemistry and Chemical Lead Optimization before beginning this course. If you are a little rusty in organic chemistry, it might be beneficial to review nucleophilic acyl substitutions reactions before beginning the peptide chemistry portion.